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Hosting Offer: Medical University of Gdansk, Intercollegiate Faculty of Biotechnology

Information about Hosting Offer

Information

RoleHosting Offer
OrganisationMedical University of Gdansk, Intercollegiate Faculty of Biotechnology
Organisation typeAcademic
CityGdańsk
HR Excellence in Research Award from the European Commissionno
National evaluation categoryA+ (excellent)
Faculty / Dept. / Division / Laboratory / Research groupMolecular Enzymology and Oncology
Websitehttps://biotech.ug.edu.pl/dzialalnosc_naukowa/zespoly_badawcze/zaklad_enzymologii_i_onkologii_molekularnej
Thematic area/fieldNZ – Life Sciences / NZ5 Human and animal non-infectious diseases
Key wordscancer research, breast cancer, translational research, tumour microenvironment, drug resistance
Short summary of activities and expertiseOur research focuses on breast cancer cell biology, with emphasis on the interactions between cancer cell and tumour microenvironment (TME). Co-evolution of tumour stroma with neoplastic cells is recognized as one of the key factors of disease progression and patients` response to the treatment. The search for new markers and mechanisms of developing resistance to available therapies is the greatest challenge of contemporary oncology. To meet the most urgent scientific problems, the research profile of our laboratory focuses on the analysis of the heterogeneity of the tumour cell population, induced by the interaction of cancer cells with the TME. Our studies include three fields of interest: 1) evolution of non-invasive, ductal carcinoma in situ to invasive breast cancers upon inflammatory stimulation, 2) involvement of FGFR family in cancer cells progression and metastasis, and 3) interaction of FGFRs with HER2 in acquisition of resistance to anti-HER2 therapies in breast cancer. The highest quality of research is ensured by the provided analyses at three complementary levels: in vitro, in vivo and clinical analyses.
Role and profile of key persons (incl. supervisor)Dr. Rafal Sadej moved from the University of Birmingham (UK) to IFB, MUG, Gdansk in 2010 after his post-doctoral studies. He will support and supervise potential POLONEZ BIS fellow.
Previous and current involvement in research and training programmesGroup members received various grants funded by the National Science Center and Foundation of Polish Science (e.g. Opus, Harmonia, Sonata Bis, Homing Plus)
Relevant publications and/or research/innovation productshttps://www.ncbi.nlm.nih.gov/search/all/?term=sadej%20r
Key research facilities, infrastructure, and equipmentWe have access to classical infrastructure required for cell biology and molecular biology studies.
Hosting arrangementsWe have access to classical infrastructure required for cell biology and molecular biology studies.
Key research facilities, infrastructure, and equipmentWe are open to new collaborations in cancer research field.
Intersectoral secondments options
Other benefits-
Candidate sought We are looking for a young and ambitious scientist with previous experience in cancer cell biology, cell signalling studies, clinical or big data analyses.
Have you hosted POLONEZ Fellows or MSCA IF Fellows before?no
Candidatures deadline 2021-10-15

Contact

First nameRafal
Last nameSadej
Email rafal.sadej@gumed.edu.pl
Phone number